Over the years, Cascade Metrix has developed multiple technologies for glucose sensing and automated blood sampling. The picture below gives a snapshot of the various technologies developed and prototyped by CM, starting with mid infrared quantum cascade laser spectroscopy based glucose sensors to a version that uses electrochemical sensors from BST Bio Sensor Technology, GmbH.
CMX's transition from infrared spectroscopy to electrochemistry based sensing was described in a research article published with the Journal of Diabetes Science and Technology. These products illustrate a transition marked by a shift from a technology-centric focus in the early days to a much more user-centric philosophy, with each iteration becoming more accurate, safe, practical, reliable and cost-effective, culminating in the current embodiment. With the current alpha prototype, bench studies using spiked blood glucose samples and live animal-connected studies have been carried out.